Wow that would be a trick.
I have a NeXTstation sitting in my basement. My first reaction was, no way the IOpener would be powerful enough. Then I reviewed the specs on the NeXT:
CPU 68030 (roughly equivalent to a Intel 486
RAM 16 MB
HD SCSI 20mb
This could be interesting. I have to unopened IOpeners gathering dust next to the NeXT. I know there was an Intel version of Nextstep called Openstep but isn't way out of date? What apps would you run? Do you have the development environment (project builder)?
Good Luck